Yes. Our Brilliant Bath is safe and effective on the glass only (avoid any contact with the frame, trim or track of the door, as these are usually made of aluminum) part of a shower door. The best way to apply it to the glass is to spray some Brilliant Bath into a damp cloth or sponge and apply it to the affected stained areas of the glass. After 2 minutes, take a clean sponge/cloth and clear cold water to remove the solution. Do not spray the doors as you will get the product on materials it's not intended to be used on.